Differin 0.1% Cream (30g) is a clinically proven topical acne treatment containing adapalene, a third-generation retinoid. It is designed to treat mild to moderate acne, including blackheads, whiteheads, papules, and pustules.
This cream formulation is particularly suitable for individuals with dry or sensitive skin, offering the same effective acne treatment as the gel but with a more hydrating, less irritating base. Suitable for adults and adolescents aged 12 years and over, it supports clearer, smoother, and healthier-looking skin with consistent use.
How It Works
Differin Cream contains adapalene 0.1%, which works by normalising skin cell turnover and preventing pores from becoming blocked — a key cause of acne.
It also helps reduce inflammation, easing redness and swelling associated with breakouts. Adapalene is stable in light and oxygen, ensuring reliable performance and improved tolerability compared to older retinoids.
Key Benefits of Differin Cream 30g (Ideal for Dry Skin)
Treats multiple types of acne (blackheads, whiteheads, inflamed spots)
Cream-based formula helps support skin hydration
Better suited for dry or sensitive skin compared to gel formulations
Helps reduce redness and inflammation
Prevents new breakouts from forming
Non-comedogenic (won’t clog pores)
Fragrance-free and gentle on skin
30g size ideal for consistent, long-term treatment
Why Choose the Cream Over the Gel?
The cream version of Differin is often preferred by those who experience dryness or irritation with acne treatments. Its emollient base helps to reduce the likelihood of excessive dryness while still delivering effective acne control.
This makes it a good option for patients with drier skin types or those new to retinoid treatments.
Important Information
Apply once daily in the evening unless directed otherwise by a healthcare professional
Mild dryness, redness, or irritation may occur initially as your skin adjusts
Use a moisturiser and daily sunscreen (SPF 30+) to protect sensitive skin
Avoid use on broken, sunburnt, or eczematous skin
Do not combine with other retinoids or harsh exfoliants unless advised
If irritation persists, reduce frequency or seek medical advice
⚠️ Note: While the cream is more suitable for dry skin, adapalene can still cause dryness or irritation, especially during the first few weeks of use. Supporting your routine with a gentle cleanser and moisturiser is recommended.









